Androgen Receptor (AR) Antibody (HRP)
169€ (20 µg)
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935106861
info@markelab.com
name
Androgen Receptor (AR) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx313223
tested applications
ELISA
Description
AR Antibody (HRP) is a Rabbit Polyclonal against AR conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Androgen Receptor (AR) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10275 |
| Gene ID | 367 |
| NCBI Accession | NP_000035.2 |
| OMIM | 300068 |
| Alias | KD,AIS,AR8,TFM,DHTR,SBMA,HYSP1,NR3C4,SMAX1,HUMARA,Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| Background | Antibody anti-AR |
| Status | RUO |
Descripción
Androgen receptor (AR) is a nuclear receptor that mediates the effects of androgens, the male sex hormones, by regulating gene expression AR plays a critical role in the development and maintenance of male sexual characteristics, as well as in the regulation of muscle mass, bone density, and red blood cell production It functions by binding to androgen hormones, such as testosterone, and translocating into the nucleus, where it interacts with DNA to regulate the transcription of target genes involved in cell growth, differentiation, and metabolism AR is essential for normal male development, including the formation of the male reproductive organs and secondary sexual characteristics During adulthood, AR helps maintain prostate function, muscle mass, and bone density Mutations in the AR gene can lead to a variety of disorders, including androgen insensitivity syndrome, prostate cancer, and certain types of hair loss, where abnormal AR signaling contributes to disease development AR is also a therapeutic target for androgen-related diseases, including prostate cancer, where therapies aim to block or modulate AR activity
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