Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody
proveedor
Abbexareference
abx430482Tested Applications
P-ELISA, WBreactivity
Mousestatus
RUOclonality
PolyclonalDescripción
APBB1 Antibody is a Goat Polyclonal antibody against APBB1.
Background
Amyloid precursor protein (APP) is a highly conserved protein. Amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are homologous of APP. APLP1 was the first identified homologue , while APLP2, was later recognized as another homologue of APP . These three proteins share significant sequence similarity and possess conserved domain structures. APLP1, a type I transmembrane protein, plays a crucial role in synaptic adhesion and synaptogenesis. Is actively involved in the formation of protein-protein complexes that serve as bridges between closely adjacent cells, facilitating cell-cell interactions and communication
Background
La proteína precursora de amiloide (APP) es una proteína altamente conservada. La proteína 1 similar al precursor de amiloide (APLP1) y la proteína 2 similar al precursor de amiloide (APLP2) son homólogas de APP. APLP1 fue el primer homólogo identificado, mientras que APLP2 fue reconocido más tarde como otro homólogo de APP. Estas tres proteínas comparten una similitud de secuencia significativa y poseen estructuras de dominio conservadas. APLP1, una proteína transmembrana de tipo I, desempeña un papel crucial en la adhesión sináptica y la sinaptogénesis. Participa activamente en la formación de complejos proteína-proteína que sirven como puentes entre células estrechamente adyacentes, facilitando las interacciones y la comunicación entre células.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Mouse
immunogen target
Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1)
host
Goat
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
APBB1
dry ice
No
availability
Shipped within 1-3 working days.
NCBI accession
NP_001155.1, NP_663722.1
note
This product is for research use only.
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