Aminopeptidase N (ANPEP) Antibody (PE)

429€ (100 tests)
Este producto es parte de ANPEP - alanyl aminopeptidase membrane
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429€ (100 tests)

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935106861
info@markelab.com
name
Aminopeptidase N (ANPEP) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx139040
tested applications
FCM

Descripción del producto

Aminopeptidase N / CD13 (ANPEP) Antibody is a Mouse Monoclonal against CD13.

Documents del producto

Instrucciones
Data sheet
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Especificaciones del producto

OMIM151530
AliasAPN,AP-M,AP-N,CD13,LAP1,P150,PEPN,Hapn,GP150,Aminopeptidase N,Alanyl aminopeptidase,Microsomal aminopeptidase,Myeloid plasma membrane glycoprotein
AvailabilityShipped within 5-12 working days.
BackgroundAntibody anti-ANPEP
BufferStabilizing PBS solution containing 15 mM sodium azide.
CategoryPrimary Antibodies
ClonalityMonoclonal
Clone IDQ678
ConjugationPE
Dry IceNo
Gene ID290
HostMouse
Immunogen TargetAminopeptidase N (ANPEP)
IsotypeIgG1
NameAminopeptidase N (ANPEP) Antibody (PE)
Price429
ProviderAbbexa
ReactivityHuman, Monkey
Recommended DilutionFCM: 20 µl/100 µl of whole blood or 106 cells. Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (2 ml) is sufficient for 100 tests.
Referenceabx139040
Size 1100 tests
StatusRUO
StorageStore in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Tested ApplicationsFCM
UniProt IDP15144

Descripcion del producto en español

Background en español

ANPEP, also known as alanyl aminopeptidase or aminopeptidase N (APN), is a key membrane-bound enzyme that plays a significant role in the hydrolysis of peptides. The gene ANPEP encodes this enzyme, which is expressed predominantly on the surface of epithelial cells in the small intestine, kidney, and other tissues, and also in certain immune cells such as monocytes, macrophages, and granulocytes. ANPEP is classified as a zinc metalloprotease, which means that its catalytic activity depends on a zinc ion in its active site. In the small intestine, ANPEP facilitates the final stages of protein digestion by cleaving neutral amino acids from the N-terminus of oligopeptides. Beyond its digestive role, ANPEP also participates in various physiological processes, including antigen processing, angiogenesis, immune response regulation, and the inflammatory response

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