Alpha Fetoprotein (AFP) Antibody (HRP)

Este producto es parte de AFP - Alpha fetoprotein
Alpha Fetoprotein (AFP) Antibody (HRP)

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µg)

Antibody anti-AFP

proveedor

Abbexa

reference

abx107960

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Polyclonal

Descripción

Alpha-Fetoprotein Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP against Alpha-Fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.


Background

Alpha-fetoprotein (AFP) is a protein that is normally produced by the liver and yolk sac of a developing fetus. It is also produced in small quantities by the fetal gastrointestinal tract. AFP levels are typically high in the fetus, but they decrease rapidly after birth and remain low in healthy adults. AFP is considered a marker of fetal development. During pregnancy, AFP levels can be measured in the mother's blood or amniotic fluid as part of prenatal screening tests. Abnormal levels of AFP may indicate certain developmental abnormalities, such as neural tube defects (e.g., spina bifida) or chromosomal abnormalities (e.g., Down syndrome).Elevated levels of AFP in the blood can also be indicative of certain types of cancer, particularly liver cancer (hepatocellular carcinoma) and certain germ cell tumors. In patients with liver cancer, AFP levels may be used as a tumor marker to monitor disease progression and response to treatment. However, it's important to note that not all cases of liver cancer produce elevated AFP levels, and AFP levels can also be elevated in other conditions, such as cirrhosis and hepatitis.AFP testing is commonly used in clinical practice for various purposes:Prenatal Screening, AFP Cancer Diagnosis and Monitoring, and Monitoring Liver Disease

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Mouse


immunogen target

Alpha Fetoprotein (AFP)


host

Rabbit


isotype

IgG


conjugation

HRP


form

Liquid


tested applications

ELISA


purity

> 95%


purification

Purified by Protein G.


recommended dilution

Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.


or code

AFP


dry ice

No


availability

Shipped within 5-10 working days.


alias

HPAFP,Alpha fetoglobulin


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