Alpha 2A Adrenergic Receptor (ADRA2A) Antibody
52€ (10 µg)
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935106861
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name
Alpha 2A Adrenergic Receptor (ADRA2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015216
tested applications
ELISA, IF/ICC
Description
Rabbit polyclonal antibody against ADRA2A protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha 2A Adrenergic Receptor (ADRA2A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/500 - 1/1000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08913 |
| Alias | ADRA2A,ADRA2,ADRA2R,Adrenergic alpha 2A receptor ,Adra-2 ,Adra-2a,ALPHA2AAR, ZNF32 |
| Background | Antibody anti-ADRA2A |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
The alpha-2 adrenergic receptors (ADRA2) are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter noradrenaline (norepinephrine) and play a role in regulating various physiological processes. There are three main subtypes of alpha-2 adrenergic receptors: Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C). ADRA2A receptors are primarily located in the central nervous system, including the brain and spinal cord. They are involved in the modulation of neurotransmitter release, particularly in the regulation of noradrenaline release. Activation of ADRA2A receptors inhibits the release of neurotransmitters such as noradrenaline, dopamine, and serotonin, leading to a decrease in sympathetic nervous system activity. ADRA2A receptors also play a role in regulating blood pressure, cognition, and mood.
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