Alpha-2 Antiplasmin (SERPINF2) Antibody

Este producto es parte de SERPINF2 - serpin family F member 2
Product Graph
260€ (100 µl)

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935106861
info@markelab.com
name
Alpha-2 Antiplasmin (SERPINF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102505
tested applications
WB, IHC, IF/ICC

Description

Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Alpha-2 Antiplasmin (SERPINF2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
PBS, pH 7.4, containing 0.02% Sodium azide, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P08697
Alias
AAP,API,PLI,A2AP,alpha2AP,Alpha-2-antiplasmin,Alpha-2-AP,Alpha-2-plasmin inhibitor,Serpin F2
Background
Antibody anti-SERPINF2
Status
RUO
Note
Concentration: 0.99 mg/ml - 

Descripción

SERPINF2, also known as alpha-2 antiplasmin (A2AP), is a crucial member of the serpin (serine protease inhibitor) family. It plays a vital role in regulating the fibrinolytic system by inhibiting plasmin, the enzyme responsible for breaking down fibrin clots. As part of the serpin superfamily, SERPINF2 helps to maintain hemostasis by preventing excessive clot breakdown, ensuring that clots remain stable during wound healing and tissue repair. First characterized in the 1970s, SERPINF2 has since been extensively studied for its role in clot stabilization and its involvement in various bleeding disorders and thrombotic conditions. It is primarily synthesized in the liver and circulates in the plasma, where it acts as a major inhibitor of fibrinolysis.

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