Alpha-2 Antiplasmin (SERPINF2) Antibody

260€ (100 µl)
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935106861
info@markelab.com
name
Alpha-2 Antiplasmin (SERPINF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102505
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Alpha-2-Plasmin Inhibitor (a2PI).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Alpha-2 Antiplasmin (SERPINF2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | PBS, pH 7.4, containing 0.02% Sodium azide, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P08697 |
Alias | AAP,API,PLI,A2AP,alpha2AP,Alpha-2-antiplasmin,Alpha-2-AP,Alpha-2-plasmin inhibitor,Serpin F2 |
Background | Antibody anti-SERPINF2 |
Status | RUO |
Note | Concentration: 0.99 mg/ml - |
Descripción
SERPINF2, also known as alpha-2 antiplasmin (A2AP), is a crucial member of the serpin (serine protease inhibitor) family. It plays a vital role in regulating the fibrinolytic system by inhibiting plasmin, the enzyme responsible for breaking down fibrin clots. As part of the serpin superfamily, SERPINF2 helps to maintain hemostasis by preventing excessive clot breakdown, ensuring that clots remain stable during wound healing and tissue repair. First characterized in the 1970s, SERPINF2 has since been extensively studied for its role in clot stabilization and its involvement in various bleeding disorders and thrombotic conditions. It is primarily synthesized in the liver and circulates in the plasma, where it acts as a major inhibitor of fibrinolysis.
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