Alpha 1B Adrenergic Receptor (ADRA1B) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
ADRA1B Antibody is a Rabbit Polyclonal against ADRA1B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha 1B Adrenergic Receptor (ADRA1B) Immunogen: Synthetic peptide of human ADRA1B. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, WB: 1/200 - 1/1000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35368 |
| Gene ID | 147 |
| Alias | ADRA1B,ADRA1,ALPHA1BAR,adrenergic alpha 1B receptor |
| Background | Antibody anti-ADRA1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
The adrenergic receptors are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter adrenaline (epinephrine) and noradrenaline (norepinephrine). The alpha-1 adrenergic receptor (ADRA1) is one subtype of adrenergic receptors, and it has three main subtypes: Alpha-1A (ADRA1A), Alpha-1B (ADRA1B), and Alpha-1D (ADRA1D). ADRA1B encodes the α1B-adrenergic receptor, predominantly expressed in the liver, heart, and cerebral blood vessels.
Related Products
ADRA1B antibody
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Ver Producto
Alpha 1B Adrenergic Receptor (ADRA1B) Antibody
Rabbit polyclonal antibody against ADRA1B protein. Immunogen region is internal.
Ver Producto
Alpha 1B Adrenergic Receptor (ADRA1B) Antibody
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, 1B and 1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Ver Producto