Alpha-1-Antitrypsin (SERPINA1) Antibody
Pida mas información
935106861
info@markelab.com
Precio
364€ (100 µg)
Antibody anti-SERPINA1
proveedor
Abbexareference
abx230337Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Alpha-1-Antitrypsin Antibody is a Rabbit Polyclonal against Alpha-1-Antitrypsin.
Background
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Alpha-1-Antitrypsin (SERPINA1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purity
≥ 95% (SDS-PAGE)
purification
Purified by immunogen affinity chromatography.
recommended dilution
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA1
dry ice
No
availability
Shipped within 5-12 working days.
alias
PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1
uniprot id
note
Concentration: 2 mg/ml - Validity: 12 months.
Quizá le pueda interesar
Alpha-1-Antiproteinase (SERPINA1) Antibody
proveedor
Abbexareference
abx101825Tested Applications
WB, IHC, IF/ICCreactivity
Ratstatus
RUOclonality
PolyclonalPolyclonal Antibody to Alpha-1-Antitrypsin (a1AT).
286€ (100 µl)
Ver másHuman Alpha-1-Antitrypsin (SERPINA1) ELISA Kit
proveedor
Abbexareference
abx150622Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Alpha-1-Antitrypsin (SERPINA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Alpha-...
689€ (96 tests)
Ver másHuman Alpha-1-Antitrypsin (SERPINA1) Protein (Active)
proveedor
Abbexareference
abx263174Tested Applications
SDS-PAGEstatus
RUOSERPINA1 is an active Human recombinant protein from Rice Grain (Oryza Sativa).
234€ (20 µg)
Ver más