Alpha-1-Antichymotrypsin (SERPINA3) Antibody
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935106861
info@markelab.com
Precio
350€ (100 µg)
Antibody anti-SERPINA3
proveedor
Abbexareference
abx230318Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
Alpha-1-Antichymotrypsin (SERPINA3) Antibody is a Mouse Monoclonal against Alpha-1-Antichymotrypsin (SERPINA3).
Background
SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
Alpha-1-Antichymotrypsin (SERPINA3)
host
Mouse
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purity
≥ 95% (SDS-PAGE)
purification
Purified by Protein A and Protein G affinity chromatography.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA3
dry ice
No
availability
Shipped within 5-12 working days.
alias
ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3
uniprot id
note
This product is for research use only.
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