Alpha-1-Antichymotrypsin (SERPINA3) Antibody

Este producto es parte de SERPINA3 - serpin family A member 3
Alpha-1-Antichymotrypsin (SERPINA3) Antibody

Pida mas información

935106861

info@markelab.com

Precio

350€ (100 µg)

Antibody anti-SERPINA3

proveedor

Abbexa

reference

abx230318

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

Alpha-1-Antichymotrypsin (SERPINA3) Antibody is a Mouse Monoclonal against Alpha-1-Antichymotrypsin (SERPINA3).


Background

SERPINA3, also known as alpha-1 antichymotrypsin (ACT), is a member of the serine protease inhibitor (serpin) superfamily. The SERPINA3 gene is located on chromosome 14 (14q32.13), in close proximity to other serpin genes, including SERPINA1, which encodes alpha-1 antitrypsin. SERPINA3 plays a crucial role in inhibiting the activity of certain proteases, particularly cathepsin G and chymotrypsin, enzymes involved in inflammation and immune responses. The protein encoded by SERPINA3 is predominantly synthesized in the liver, but it is also expressed in various other tissues, including the brain, lungs, and immune cells. SERPINA3 has been implicated in a variety of physiological and pathological processes, such as inflammation, tissue remodeling, and the acute phase response. It is also known for its association with neurodegenerative diseases, particularly Alzheimer's disease, where it is found in amyloid plaques.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

Alpha-1-Antichymotrypsin (SERPINA3)


host

Mouse


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purity

≥ 95% (SDS-PAGE)


purification

Purified by Protein A and Protein G affinity chromatography.


buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.


size 1

100 µg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

SERPINA3


dry ice

No


availability

Shipped within 5-12 working days.


alias

ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3


note

This product is for research use only.


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