Alpha-1-Acid Glycoprotein 1 (ORM1) Antibody
195€ (20 µl)
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935106861
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name
Alpha-1-Acid Glycoprotein 1 (ORM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001490
tested applications
ELISA, WB
Description
Orosomucoid 1 Antibody is a Rabbit Polyclonal antibody against Orosomucoid 1. Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (Orosomucoid 1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. Orosomucoid 1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in human plasma which may be due to the glycosylation of Orosomucoid 1 or the dimer formation of the protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-1-Acid Glycoprotein 1 (ORM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P02763 |
| Gene ID | 5004 |
| NCBI Accession | NP_000598.2 |
| OMIM | 138600 |
| Alias | Alpha-1-Acid Glycoprotein/orm1,Orosomucoid-1,OMD 1,Orosomucoid 1 |
| Background | Antibody anti-ORM1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Alpha-1-Acid Glycoprotein (ORM1), also known as orosomucoid, is an acute-phase plasma protein predominantly synthesized in the liver. ORM1 is a part of the acute-phase response, where its levels in the blood increase in response to inflammation, infection, or injury.It is a 43-44 kDa glycoprotein well known as a one of the major acute phase proteins in humans, rats and many other spices The carbohydrate content represents 45% of the molecular weight attached in the form of five to six highly sialylated complex-type-N-linked glycans.ORM1 has since been studied extensively for its role in immune regulation, drug binding, and inflammation.
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