Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027462
tested applications
ELISA, WB, IHC
Description
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10696 |
| Alias | GCAP,ALPPL,ALPPL2,ALP-1,Alkaline phosphatase Nagao isozyme,Alkaline phosphatase, placental-like,Germ cell alkaline phosphatase |
| Background | Antibody anti-ALPG |
| Status | RUO |
Descripción
Alkaline phosphatase, germ cell (ALPG), is an isoenzyme of alkaline phosphatase predominantly expressed in germ cells. It plays a crucial role in dephosphorylation processes, which are vital for metabolic pathways and cellular signaling. ALPG is part of a family of enzymes known for their ability to remove phosphate groups from molecules such as nucleotides, proteins, and alkaloids in an alkaline environment. ALPG is notably expressed in certain tissues, including the testes and germ cells, where it contributes to the regulation of phosphate metabolism and possibly supports spermatogenesis and other germ-cell-specific functions. Due to its unique tissue-specific expression, ALPG serves as a biomarker in various clinical contexts, such as diagnosing germ cell tumors or studying germ cell biology. Understanding its regulatory mechanisms and interactions provides insights into developmental and reproductive processes.
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Alkaline Phosphatase, Placental Like Protein 2 (ALPPL2) Antibody
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.
Ver Producto