ALG11, Alpha-1,2-Mannosyltransferase (ALG11) Antibody

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Description
ALG11 Antibody is a Rabbit Polyclonal against ALG11.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ALG11, Alpha-1,2-Mannosyltransferase (ALG11) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1/200 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q2TAA5 |
Gene ID | 440138 |
Background | Antibody anti-ALG11 |
Status | RUO |
Descripción
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This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase has been identified on chromosome 19.
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