Agouti-Signaling Protein (ASIP) Antibody
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Description
ASIP Antibody is a Rabbit Polyclonal antibody against ASIP. In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may affect the quality of hair pigmentation, act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Agouti-Signaling Protein (ASIP) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42127 |
| Gene ID | 434 |
| NCBI Accession | NP_001663.2 |
| Background | Antibody anti-ASIP |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Agouti-Signaling Protein (ASIP) Antibody
ASIP Antibody is a Rabbit Polyclonal antibody against ASIP. In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may affect the quality of hair pigmentation, act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes.
Ver Producto