Aggrecan Core Protein (ACAN) Antibody

Este producto es parte de ACAN - Aggrecan Core Protein
Aggrecan Core Protein (ACAN) Antibody

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935106861

info@markelab.com

Precio

286€ (100 µl)

Antibody anti-ACAN

proveedor

Abbexa

reference

abx100127

Tested Applications

WB, IHC, IF/ICC

reactivity

Rat

status

RUO

clonality

Polyclonal

Descripción

Polyclonal Antibody to Aggrecan (AGC).

Background

The ACAN gene encodes the protein Aggrecan, also known as cartilage-specific proteoglycan core protein or chondroitin sulfate proteoglycan 1. As a member of the lectican family, Aggrecan is a crucial component of the extracellular matrix in cartilaginous tissue, providing resistance to compression. It is a proteoglycan modified with large carbohydrates, with the human form consisting of 2316 amino acids and exhibiting multiple isoforms due to alternative splicing. Aggrecan derives its name from its ability to form large aggregates in cartilage. Mutations in this gene may lead to skeletal dysplasia and spinal degeneration. Various transcript variants encoding different protein isoforms have been identified through alternative splicing.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Rat

immunogen target

Aggrecan Core Protein (ACAN)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

WB, IHC, IF/ICC

purification

Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.

recommended dilution

WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.

buffer

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.

size 1

100 µl

size 2

200 µl

size 3

1 ml

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ACAN

dry ice

No

availability

Shipped within 5-7 working days.

alias

AGC1,AGCAN,CSPG1,CSPGCP,MSK16,Cartilage-specific proteoglycan core protei,CSPC,Chondroitin sulfate proteoglycan core protein 1

uniprot id

https://www.uniprot.org/uniprotkb/P07897

gene id

https://www.ncbi.nlm.nih.gov/gene/58968

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