Afadin- And Alpha-Actinin-Binding Protein (SSX2IP) Antibody
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Description
Synovial Sarcoma, X Breakpoint 2 Interacting Protein Antibody is a Rabbit Polyclonal antibody against Synovial Sarcoma, X Breakpoint 2 Interacting Protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Afadin- And Alpha-Actinin-Binding Protein (SSX2IP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y2D8 |
| Gene ID | 117178 |
| NCBI Accession | NP_001159765.1, NM_001166293.1 |
| OMIM | 608690 |
| Background | Antibody anti-SSX2IP |
| Status | RUO |
Descripción
Related Products
SSX2IP antibody
Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions(AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin(By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling(By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome(PubMed:23816619, PubMed:26545777). Involved in ciliogenesis(PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia(PubMed:24356449).
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Afadin- And Alpha-Actinin-Binding Protein (SSX2IP) Antibody
Synovial Sarcoma, X Breakpoint 2 Interacting Protein Antibody is a Rabbit Polyclonal antibody against Synovial Sarcoma, X Breakpoint 2 Interacting Protein.
Ver ProductoAfadin- And Alpha-Actinin-Binding Protein (SSX2IP) Antibody
SSX2IP Antibody is a Rabbit Polyclonal against SSX2IP.
Ver Producto