AF4/FMR2 Family Member 2 (AFF2) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
AF4/FMR2 Family Member 2 (AFF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030062
tested applications
ELISA, WB
Description
This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | AF4/FMR2 Family Member 2 (AFF2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51816 |
| Alias | FMR2,OX19 |
| Background | Antibody anti-AFF2 |
| Status | RUO |
Descripción
The AFF (AF4/FMR2) family member refers to a group of proteins associated with various cellular functions, particularly in the context of gene regulation and transcriptional control. The name "AFF" comes from the fusion partner of MLL (Mixed-Lineage Leukemia) in certain leukemia cases. AFF2 known as FMR2 (Fragile X mental retardation 2), mutations in this gene are linked to Fragile X syndrome.
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