Adrenergic Receptor Alpha 2B (ADRA2B) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Adrenergic Receptor Alpha 2B (ADRA2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013413
tested applications
ELISA, IF/ICC
Description
Rabbit polyclonal antibody against Adrenergic Receptor alpha 2B protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adrenergic Receptor Alpha 2B (ADRA2B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/100 - 1/500, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P18089 |
| Alias | ADRA2B,ADRA2L1,ADRA2RL1,Adrenergic alpha2B- receptor class III,Adra-2b,alpha2B,ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR |
| Background | Antibody anti-ADRA2B |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
The alpha-2 adrenergic receptors (ADRA2) are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter noradrenaline (norepinephrine) and play a role in regulating various physiological processes. There are three main subtypes of alpha-2 adrenergic receptors: Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C). ADRA2B receptors are found in various tissues, including vascular smooth muscle, the heart, and the pancreas. They are involved in the regulation of vascular tone, cardiac function, and insulin secretion. Activation of ADRA2B receptors leads to vasoconstriction, decreased heart rate, and inhibition of insulin release from pancreatic beta cells. ADRA2B receptors also play a role in modulating neurotransmitter release in the central nervous system.ADRA2C receptors are widely distributed in the central nervous system, as well as in peripheral tissues such as vascular smooth muscle and the heart. They play a role in regulating sympathetic nervous system activity, vascular tone, and cardiac function. Activation of ADRA2C receptors leads to vasoconstriction and decreased heart rate. ADRA2C receptors also modulate neurotransmitter release in the central nervous system.
Related Products
ADRA2B-Specific antibody
ADRA2B, also named as ADRA2L1 and ADRA2RL1, belongs to the G-protein coupled receptor 1 family. ADRA2B mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The antibody is specific to ADRA2B.
Ver ProductoADRA2B antibody
ADRA2B, also named as ADRA2L1 and ADRA2RL1, belongs to the G-protein coupled receptor 1 family. ADRA2B mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The antibody is specific to ADRA2B.
Ver Producto