ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) Antibody
Pida mas información
935106861
info@markelab.com
Precio
299€ (50 µl)
Antibody anti-CD38
proveedor
Abbexareference
abx402405Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human CD38.
Background
CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 1 (CD38)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
expression
Recombinant
purification
Purified by affinity chromatography.
recommended dilution
WB: 1/500 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD38
dry ice
No
availability
Shipped within 5-10 working days.
alias
ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1
uniprot id
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