Adiponectin Receptor 2 (ADIPOR2) Antibody
637€ (100 µl)
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Name
Adiponectin Receptor 2 (ADIPOR2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx110860
Tested Applications
ELISA, WB, IHC, IP
Description
Adiponectin Receptor 2 Antibody is a Rabbit Polyclonal antibody against Adiponectin Receptor 2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adiponectin Receptor 2 (ADIPOR2) Immunogen: Human ADIPOR2. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/1000, IP: 0.5-4 µg. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86V24 |
| Gene ID | 79602 |
| OMIM | 607946 |
| Alias | ACDCR2,PAQR2 |
| Background | Antibody anti-ADIPOR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
The adiponectin receptor (ADIPOR) is a cell surface receptor that mediates the biological effects of adiponectin, a protein hormone secreted by adipose tissue. There are two known types of adiponectin receptors, named adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2). These receptors are encoded by the ADIPOR1 and ADIPOR2 genes, respectively. Adiponectin receptors belong to the class of seven-transmembrane domain receptors, also known as G protein-coupled receptors (GPCRs). They have an extracellular N-terminus, seven transmembrane helices, and an intracellular C-terminus. ADIPOR1 and ADIPOR2 exhibit distinct tissue distribution and signal transduction mechanisms. Adiponectin receptors specifically bind to adiponectin, allowing the hormone to exert its effects on target cells. Adiponectin exists in different oligomeric forms, including trimeric, hexameric, and high-molecular-weight complexes, and can interact with both ADIPOR1 and ADIPOR2. Activation of adiponectin receptors triggers intracellular signaling pathways that regulate various physiological processes, including glucose metabolism, fatty acid oxidation, insulin sensitivity, and anti-inflammatory responses.
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