Human Adiponectin Receptor 2 (ADIPOR2) Protein

Este producto es parte de ADIPOR - Adiponectin receptor
Human Adiponectin Receptor 2 (ADIPOR2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ADIPOR2

proveedor

Abbexa

reference

abx065173

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Adiponectin Receptor 2 (ADIPOR2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

The adiponectin receptor (ADIPOR) is a cell surface receptor that mediates the biological effects of adiponectin, a protein hormone secreted by adipose tissue. There are two known types of adiponectin receptors, named adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2). These receptors are encoded by the ADIPOR1 and ADIPOR2 genes, respectively. Adiponectin receptors belong to the class of seven-transmembrane domain receptors, also known as G protein-coupled receptors (GPCRs). They have an extracellular N-terminus, seven transmembrane helices, and an intracellular C-terminus. ADIPOR1 and ADIPOR2 exhibit distinct tissue distribution and signal transduction mechanisms. Adiponectin receptors specifically bind to adiponectin, allowing the hormone to exert its effects on target cells. Adiponectin exists in different oligomeric forms, including trimeric, hexameric, and high-molecular-weight complexes, and can interact with both ADIPOR1 and ADIPOR2. Activation of adiponectin receptors triggers intracellular signaling pathways that regulate various physiological processes, including glucose metabolism, fatty acid oxidation, insulin sensitivity, and anti-inflammatory responses.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Adiponectin Receptor 2 (ADIPOR2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 47.8 kDa Observed MW: 48 kDa (SDS-PAGE) Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Asn2-Gly155 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ADIPOR2


dry ice

No


availability

Shipped within 5-12 working days.


alias

ACDCR2,PAQR2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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