Adiponectin Receptor 1 (ADIPOR1) Antibody

Este producto es parte de ADIPOR - Adiponectin receptor
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Adiponectin Receptor 1 (ADIPOR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038213
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the ADIPOR1 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdiponectin Receptor 1 (ADIPOR1)
HostRabbit
ReactivityHuman
Recommended DilutionELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by Protein A/G column chromatography.
Size 1100 µg
Size 21 mg
FormLyophilized
Tested ApplicationsELISA, WB, IHC
BufferPrior to lyophilization: 0.02% NaN3.
AvailabilityShipped within 7-15 working days.
StorageStore at -20 °C. Avoid repeated freeze/thaw cycles.
Dry IceNo
NCBI AccessionNM_004797
AliasACDCR1,CGI-45,CGI45,PAQR1
BackgroundAntibody anti-ADIPOR1
StatusRUO
NoteConcentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

Descripción

The adiponectin receptor (ADIPOR) is a cell surface receptor that mediates the biological effects of adiponectin, a protein hormone secreted by adipose tissue. There are two known types of adiponectin receptors, named adiponectin receptor 1 (ADIPOR1) and adiponectin receptor 2 (ADIPOR2). These receptors are encoded by the ADIPOR1 and ADIPOR2 genes, respectively. Adiponectin receptors belong to the class of seven-transmembrane domain receptors, also known as G protein-coupled receptors (GPCRs). They have an extracellular N-terminus, seven transmembrane helices, and an intracellular C-terminus. ADIPOR1 and ADIPOR2 exhibit distinct tissue distribution and signal transduction mechanisms. Adiponectin receptors specifically bind to adiponectin, allowing the hormone to exert its effects on target cells. Adiponectin exists in different oligomeric forms, including trimeric, hexameric, and high-molecular-weight complexes, and can interact with both ADIPOR1 and ADIPOR2. Activation of adiponectin receptors triggers intracellular signaling pathways that regulate various physiological processes, including glucose metabolism, fatty acid oxidation, insulin sensitivity, and anti-inflammatory responses.
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