Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody (PE / Cyanine 7)
104€ (50 tests)
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Name
Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody (PE / Cyanine 7)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx228088
Tested Applications
FCM
Description
F4/80 antibody (PE / Cyanine 7) is a Rat monoclonal antibody against F4/80.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adhesion G Protein-Coupled Receptor E1 (ADGRE1) |
| Host | Rat |
| Reactivity | Mouse |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/782 |
| Clonality | Monoclonal |
| Conjugation | PE / Cyanine 7 |
| Isotype | IgG2b |
| Size 1 | 50 tests |
| Size 2 | 25 µg |
| Size 3 | 100 tests |
| Size 4 | 100 µg |
| Size 5 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q61549 |
| Gene ID | 13733 |
| Alias | ADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3 |
| Background | Antibody anti-ADGRE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.
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