Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx232922
tested applications
ELISA, WB, IHC
Description
F4/80 Antibody is a Rabbit Polyclonal against F4/80.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor E1 (ADGRE1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14246 |
| Gene ID | 2015 |
| OMIM | 600493 |
| Alias | ADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3 |
| Background | Antibody anti-ADGRE1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.
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