Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody

Este producto es parte de ADGRE - Adhesion G protein-coupled receptor E
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364€ (100 µg)

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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor E1 (ADGRE1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx232922
tested applications
ELISA, WB, IHC

Description

F4/80 Antibody is a Rabbit Polyclonal against F4/80.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdhesion G Protein-Coupled Receptor E1 (ADGRE1)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionWB: 1/500 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity≥ 95% (SDS-PAGE)
PurificationPurified by immunogen affinity chromatography.
Size 1100 µg
FormLiquid
Tested ApplicationsELISA, WB, IHC
BufferPBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
AvailabilityShipped within 5-12 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ14246
Gene ID2015
OMIM600493
AliasADGRE1,EMR1,EGF-like module-containing, mucin-like hormone receptor-like 1,TM7LN3
BackgroundAntibody anti-ADGRE1
StatusRUO
NoteConcentration: 2 mg/ml - Validity: 12 months.

Descripción

ADGRE1, also known as EMR1 (Epidermal Growth Factor-Like Module Containing Mucin-Like Hormone Receptor 1), is a member of the adhesion G protein-coupled receptor family expressed predominantly in macrophages and other immune cells. It plays a significant role in immune regulation, particularly in processes like phagocytosis and inflammatory responses. ADGRE1 is characterized by extracellular EGF-like domains that mediate cell-cell and cell-matrix interactions. It has been implicated in the regulation of tissue homeostasis and macrophage activation in various inflammatory conditions. Dysregulation of ADGRE1 is associated with autoimmune diseases and chronic inflammation, highlighting its role in modulating immune cell functions and maintaining immune equilibrium.

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