Adhesion G Protein-Coupled Receptor B2 (ADGRB2) Antibody (FITC)
169€ (20 µg)
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Name
Adhesion G Protein-Coupled Receptor B2 (ADGRB2) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx334597
Description
ADGRB2 Antibody (FITC) is a Rabbit Polyclonal against ADGRB2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adhesion G Protein-Coupled Receptor B2 (ADGRB2) Immunogen: Recombinant Human Adhesion G protein-coupled receptor B2 protein (1371-1545AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60241 |
| Gene ID | 576 |
| Alias | ADGRB2,BAI2 |
| Background | Antibody anti-ADGRB2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADGRB2, or BAI2, is another member of the adhesion GPCR family with prominent expression in the central nervous system and vascular endothelial cells. It is involved in modulating vascular stability and angiogenesis through interactions with extracellular matrix proteins and intracellular signaling pathways. ADGRB2 is implicated in maintaining the blood-brain barrier and regulating vascular integrity, particularly during stress or injury. It also contributes to neurodevelopmental processes by influencing synapse formation and neuronal connectivity. Mutations or dysregulation of ADGRB2 have been linked to vascular abnormalities and potential roles in neurodegenerative diseases. Its functional overlap and synergy with other members of the ADGRB family emphasize its role in maintaining vascular and neural homeostasis.
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