Adhesion G Protein-Coupled Receptor B2 (ADGRB2) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor B2 (ADGRB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx338815
tested applications
ELISA, WB, IF/ICC
Description
ADGRB2 Antibody is a Rabbit Polyclonal against ADGRB2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor B2 (ADGRB2) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60241 |
| Gene ID | 576 |
| Alias | ADGRB2,BAI2 |
| Background | Antibody anti-ADGRB2 |
| Status | RUO |
Descripción
ADGRB2, or BAI2, is another member of the adhesion GPCR family with prominent expression in the central nervous system and vascular endothelial cells. It is involved in modulating vascular stability and angiogenesis through interactions with extracellular matrix proteins and intracellular signaling pathways. ADGRB2 is implicated in maintaining the blood-brain barrier and regulating vascular integrity, particularly during stress or injury. It also contributes to neurodevelopmental processes by influencing synapse formation and neuronal connectivity. Mutations or dysregulation of ADGRB2 have been linked to vascular abnormalities and potential roles in neurodegenerative diseases. Its functional overlap and synergy with other members of the ADGRB family emphasize its role in maintaining vascular and neural homeostasis.
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