Adenylate Kinase 1 (AK1) Antibody
169€ (20 µl)
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Name
Adenylate Kinase 1 (AK1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx322500
Tested Applications
ELISA, WB, IHC
Description
AK1 Antibody is a Rabbit Polyclonal against AK1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Kinase 1 (AK1) Immunogen: Recombinant human Adenylate kinase isoenzyme 1 protein (1-194AA). |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P00568 |
| Gene ID | 203 |
| OMIM | 103000 |
| Alias | HTL-S-58j |
| Background | Antibody anti-AK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AK1 is a cytosolic enzyme that plays a critical role in cellular energy homeostasis by catalyzing the reversible transfer of a phosphate group between ADP molecules to form ATP and AMP. Highly expressed in skeletal and cardiac muscle, AK1 facilitates rapid ATP turnover, essential for high-energy-consuming tissues. AK1 mutations are associated with myopathies, hemolytic anemia, and impaired energy metabolism. Its function is critical in maintaining the ATP/ADP ratio during stress and exercise, supporting glycolysis and oxidative phosphorylation. AK1 is also involved in signaling pathways related to cellular stress responses and proliferation. Studies have shown its role in modulating metabolic responses during hypoxia.
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