Adenylate Cyclase 9 (ADCY9) Antibody

Background

ADCY9 is expressed in multiple tissues, including the lungs, heart, and immune cells. Unlike calcium-sensitive isoforms, ADCY9 is activated by forskolin and G-protein signaling but is inhibited by calcium. It is crucial for cAMP-mediated signal transduction, particularly in immune response and cardiovascular regulation. ADCY9 has been linked to pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), and cardiovascular disorders. Its modulation of cAMP levels influences cellular responses to hormones, neurotransmitters, and inflammatory signals.