Adenylate Cyclase 9 (ADCY9) Antibody
221€ (50 µg)
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Name
Adenylate Cyclase 9 (ADCY9) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx324456
Tested Applications
ELISA, WB, IHC
Description
ADCY9 Antibody is a Rabbit Polyclonal against ADCY9.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 9 (ADCY9) Immunogen: Synthesized peptide derived from the N-terminal region of human A Cyclase IX. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60503 |
| Gene ID | 115 |
| Alias | AC9,ACIX |
| Background | Antibody anti-ADCY9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY9 is expressed in multiple tissues, including the lungs, heart, and immune cells. Unlike calcium-sensitive isoforms, ADCY9 is activated by forskolin and G-protein signaling but is inhibited by calcium. It is crucial for cAMP-mediated signal transduction, particularly in immune response and cardiovascular regulation. ADCY9 has been linked to pulmonary diseases, such as chronic obstructive pulmonary disease (COPD), and cardiovascular disorders. Its modulation of cAMP levels influences cellular responses to hormones, neurotransmitters, and inflammatory signals.
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