Adenylate Cyclase 6 (ADCY6) Antibody

Este producto es parte de ADCY - Adenylate Cyclase Type
Adenylate Cyclase 6 (ADCY6) Antibody
780€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Adenylate Cyclase 6 (ADCY6) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx171088
Tested Applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Adenylate Cyclase 6 (ADCY6)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
AC6,LCCS8,Adenylate cyclase type 6
Background
Antibody anti-ADCY6
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

ADCY6 is a transmembrane enzyme expressed abundantly in the cardiovascular system and kidneys. It is essential for cAMP production in response to G-protein-coupled receptor activation and is regulated by mechanical stimuli and forskolin. ADCY6 plays a key role in cardiac contraction, vascular smooth muscle relaxation, and renal water regulation. Disruption of ADCY6 function has been associated with cardiovascular diseases, including hypertension and heart failure, due to impaired cAMP-mediated signaling pathways in cardiac tissues.

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