Adenylate Cyclase 3 (ADCY3) Antibody
364€ (100 µg)
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935106861
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name
Adenylate Cyclase 3 (ADCY3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230156
tested applications
ELISA, WB, IHC, IF/ICC
Description
ADCY3 Antibody is a Rabbit Polyclonal against ADCY3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adenylate Cyclase 3 (ADCY3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60266 |
| Gene ID | 109 |
| OMIM | 600291 |
| Alias | AC-III,AC3,BMIQ19,Adenylate cyclase type 3 |
| Background | Antibody anti-ADCY3 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ADCY3 is a key effector enzyme involved in the production of cAMP and is localized predominantly in the olfactory epithelium and brain regions. It mediates odorant signaling in olfactory sensory neurons, playing a critical role in the sense of smell. ADCY3 is activated by G-proteins and modulated by calcium ions. Beyond olfaction, ADCY3 is implicated in energy balance, glucose metabolism, and obesity, as its dysfunction has been linked to obesity and insulin resistance. It also participates in cellular signaling related to growth and development.
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