Adapter Molecule Crk (CRK) Antibody
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935106861
info@markelab.com
Precio
364€ (100 µg)
Antibody anti-CRK
proveedor
Abbexareference
abx231981Tested Applications
ELISA, WB, IHCreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
CRK Antibody is a Rabbit Polyclonal against CRK.
Background
Proto-oncogene c-Crk (CRK) is an adaptor protein that plays a critical role in various cellular processes, including signal transduction, cellular migration, and proliferation. It does not have enzymatic activity but acts by interacting with other proteins via its SH2 and SH3 domains. These interactions are crucial for the transmission of signals from receptor tyrosine kinases (RTKs) and other cellular receptors, which control processes like cell growth and differentiation. CRK is involved in many pathways, including those related to cell adhesion, cytoskeletal rearrangement, and survival. Its involvement in regulating these processes makes it a key player in cancer biology, where it can function as an oncogene when dysregulated.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
Adapter Molecule Crk (CRK)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purity
≥ 95% (SDS-PAGE)
purification
Purified by immunogen affinity chromatography.
recommended dilution
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CRK
dry ice
No
availability
Shipped within 5-12 working days.
alias
CRK, CRKII, p38, v-crk avian sarcoma virus CT10 oncogene homolog, CRK proto-oncogene
uniprot id
note
Concentration: 2 mg/ml - Validity: 12 months.
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