ADAMTS-Like Protein 3 (ADAMTSL3) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
ADAMTS-Like Protein 3 (ADAMTSL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037300
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the ADAMTSL3 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ADAMTS-Like Protein 3 (ADAMTSL3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Punctin-2,ADAMTSL-3 |
| Background | Antibody anti-ADAMTSL3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ADAMTSL3 belongs to the ADAMTS-like family and is involved in ECM maintenance and fibrillin microfibril assembly. It is structurally similar to ADAMTS proteins but lacks enzymatic activity, instead functioning as a structural regulator of the ECM. ADAMTSL3 interacts with fibrillin-1 and latent TGF-β binding proteins, thus influencing TGF-β signaling pathways, which are crucial for tissue growth and repair. Alterations in ADAMTSL3 expression have been implicated in connective tissue disorders and diseases affecting the skeletal system. Recent studies suggest its role in the regulation of tissue remodeling processes and its association with ECM-related pathologies, including fibrosis.
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