ADAM Metallopeptidase With Thrombospondin Type 1 Motif 9 (ADAMTS9) Antibody (FITC)

169€ (20 µg)
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935106861
info@markelab.com
name
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 9 (ADAMTS9) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx316559
Description
ADAMTS9 Antibody (FITC) is a Rabbit Polyclonal against ADAMTS9 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 9 (ADAMTS9) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | FITC |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9P2N4 |
Gene ID | 56999 |
NCBI Accession | NP_001305710.1, NM_001318781.1 |
OMIM | 605421 |
Alias | KIAA1312, Type 1 Motif 9,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 9,ADAMTS-9,ADAM-TS9 |
Background | Antibody anti-ADAMTS9 |
Status | RUO |
Descripción
ADAMTS9 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 9) is a member of the ADAMTS family of proteases. Like other members of the ADAMTS family, ADAMTS9 contains characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS9 is expressed in various tissues, including the brain, heart, kidney, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling.ADAMTS9 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, such as proteoglycans and collagens. Additionally, ADAMTS9 has been implicated in angiogenesis, wound healing, and inflammation.Dysregulation of ADAMTS9 has been associated with several diseases and conditions. For instance, ADAMTS9 has been linked to cancer, where it may affect tumor growth, invasion, and metastasis by influencing the ECM and angiogenesis. Moreover, mutations in the ADAMTS9 gene have been associated with certain developmental disorders and connective tissue diseases.
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