ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Primary Antibodies
Polyclonal
Human
ADAM Metallopeptidase Domain 17 (ADAM17)
Rabbit
Unconjugated
Liquid
ELISA, WB
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
ADAM17
No
Shipped within 5-10 working days.
CSVP, CD156B, TACE,TNF-Alpha Convertase,TNF-Alpha Converting enzyme,adam-17
This product is for research use only.
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Ver másThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are mem...
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