Acylglycerol Kinase (AGK) Antibody
442€ (200 µl)
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935106861
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name
Acylglycerol Kinase (AGK) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432131
tested applications
P-ELISA, WB
Description
Acylglycerol kinase Antibody is a Goat Polyclonal antibody against Acylglycerol kinase.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Acylglycerol Kinase (AGK) Immunogen: abx615246 - C-Terminus: CDPRKREQMLTSP |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 55750, 69923 |
| NCBI Accession | NP_060708.1 |
| Alias | CATC5,CTRCT38,MTDPS10,MULK |
| Background | Antibody anti-AGK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Acylglycerol kinase (AGK) is a mitochondrial enzyme that catalyzes the phosphorylation of monoacylglycerol and diacylglycerol to produce lysophosphatidic acid (LPA) and phosphatidic acid (PA), which are critical intermediates in lipid metabolism, membrane biosynthesis, and intracellular signaling pathways. AGK also plays an essential role in the assembly and stability of mitochondrial respiratory chain supercomplexes, ensuring efficient oxidative phosphorylation and ATP production. This dual function underscores its importance in both energy metabolism and lipid signaling. Mutations in the AGK gene are associated with Sengers syndrome, a rare mitochondrial disorder characterized by cardiomyopathy, cataracts, skeletal myopathy, and lactic acidosis. Dysregulation of AGK has also been linked to cancer progression, where it enhances tumor growth by modulating lipid-derived signaling molecules and energy homeostasis. AGK is gaining attention as a therapeutic target in cancer and mitochondrial dysfunction, with research exploring its potential in restoring metabolic balance and energy efficiency.
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