Acyl-Coenzyme A Thioesterase 9, Mitochondrial (ACOT9) Antibody
357.5€ (100 µg)
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935106861
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name
Acyl-Coenzyme A Thioesterase 9, Mitochondrial (ACOT9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038000
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACOT9 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-Coenzyme A Thioesterase 9, Mitochondrial (ACOT9) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ACATE2,CGI-16,MTACT48,MT-ACT48 |
| Background | Antibody anti-ACOT9 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ACOT9 is a mitochondrial enzyme that hydrolyzes long-chain acyl-CoA esters into free fatty acids and CoA, playing a significant role in lipid metabolism and energy regulation. It is highly expressed in metabolically active tissues such as the liver, skeletal muscle, and heart, where it regulates the intracellular levels of acyl-CoA and ensures the balance between fatty acid oxidation and lipid synthesis. ACOT9 is critical for maintaining CoA availability within mitochondria, preventing the buildup of acyl-CoA intermediates that can disrupt cellular metabolism. It is also involved in the regulation of lipid signaling molecules and metabolic responses to fasting or increased energy demand. Dysregulation of ACOT9 activity has been associated with metabolic disorders, including obesity, type 2 diabetes, and mitochondrial dysfunction, underscoring its importance in systemic energy balance and metabolic health.
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