Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3) Antibody

Este producto es parte de ACOX - Acyl Coenzyme A Oxidase
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169€ (20 µg)

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935106861
info@markelab.com
name
Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302978
tested applications
ELISA

Description

ACOX3 Antibody is a Rabbit Polyclonal against ACOX3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O15254
Gene ID
8310
NCBI Accession
NP_001095137.1, NM_001101667.1, NP_003492.2, NM_003501.2
OMIM
603402
Alias
ACOX3
Background
Antibody anti-ACOX3
Status
RUO

Descripción

Acyl-CoA oxidases (ACOXs) are crucial enzymes involved in the first step of peroxisomal β-oxidation, a pathway responsible for the breakdown of very-long-chain fatty acids (VLCFAs), branched-chain fatty acids, and bile acid intermediates. ACOXs catalyze the oxidation of acyl-CoA to trans-2-enoyl-CoA, producing hydrogen peroxide in the process. ACOX catalyzes the first step of the beta-oxidation pathway within peroxisomes. It oxidizes long-chain acyl-CoA molecules, removing two carbons from the fatty acid chain to produce trans-2-enoyl-CoA. This reaction involves the transfer of electrons to molecular oxygen, leading to the formation of hydrogen peroxide (H2O2). Fatty acid beta-oxidation is a crucial pathway for the catabolism of fatty acids, which are important sources of energy for cells. By breaking down fatty acids into acetyl-CoA units, beta-oxidation provides substrates for energy production through processes such as the citric acid cycle and oxidative phosphorylation. ACOX3 oxidizes branched-chain fatty acids, particularly pristanoyl-CoA.
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