Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3) Antibody

Este producto es parte de ACOX - Acyl Coenzyme A Oxidase
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286€ (100 µl)

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935106861
info@markelab.com
name
Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx175241
tested applications
WB, IHC, IF/ICC

Description

Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3) Antibody is a Rabbit Polyclonal antibody against Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl Coenzyme A Oxidase 3, Pristanoyl (ACOX3)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ACOX3
Background
Antibody anti-ACOX3
Status
RUO

Descripción

Acyl-CoA oxidases (ACOXs) are crucial enzymes involved in the first step of peroxisomal β-oxidation, a pathway responsible for the breakdown of very-long-chain fatty acids (VLCFAs), branched-chain fatty acids, and bile acid intermediates. ACOXs catalyze the oxidation of acyl-CoA to trans-2-enoyl-CoA, producing hydrogen peroxide in the process. ACOX catalyzes the first step of the beta-oxidation pathway within peroxisomes. It oxidizes long-chain acyl-CoA molecules, removing two carbons from the fatty acid chain to produce trans-2-enoyl-CoA. This reaction involves the transfer of electrons to molecular oxygen, leading to the formation of hydrogen peroxide (H2O2). Fatty acid beta-oxidation is a crucial pathway for the catabolism of fatty acids, which are important sources of energy for cells. By breaking down fatty acids into acetyl-CoA units, beta-oxidation provides substrates for energy production through processes such as the citric acid cycle and oxidative phosphorylation. ACOX3 oxidizes branched-chain fatty acids, particularly pristanoyl-CoA.
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