Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) Antibody
364€ (100 µg)
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935106861
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name
Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230114
tested applications
ELISA, WB, IHC
Description
ACSS3 Antibody is a Rabbit Polyclonal against ACSS3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Synthetase Short-Chain Family Member 3 (ACSS3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H6R3 |
| Gene ID | 79611 |
| OMIM | 614356 |
| Alias | ACSS3 |
| Background | Antibody anti-ACSS3 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ACSS3 is a mitochondrial enzyme that activates short-chain fatty acids, such as propionate and acetate, converting them into their CoA derivatives for use in metabolic pathways like the TCA cycle and gluconeogenesis. It is predominantly expressed in the liver and kidneys, where it supports energy production and metabolic flexibility, particularly during fasting or other energy-demanding states. ACSS3 is involved in the metabolism of short-chain fatty acids derived from the gut microbiota, linking microbial activity to host energy homeostasis. Its activity ensures the efficient utilization of short-chain fatty acids, preventing their accumulation and associated metabolic imbalances. Dysregulation of ACSS3 has been associated with metabolic disorders, including propionic acidemia and other fatty acid metabolism-related conditions, emphasizing its importance in maintaining energy balance and metabolic health.
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