Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody (HRP)
169€ (20 µg)
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Name
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx312216
Tested Applications
ELISA
Description
ACSL5 Antibody (HRP) is a Rabbit Polyclonal against ACSL5 conjugated to HRP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Immunogen: Recombinant human Long-chain-fatty-acid--CoA ligase 5 protein (33-683AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULC5 |
| Gene ID | 51703 |
| NCBI Accession | NP_057318.2, NM_016234.3, NP_976313.1, NM_203379.1 |
| OMIM | 605677 |
| Alias | ACS2,ACS5,DIAR13,FACL5 |
| Background | Antibody anti-ACSL5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACSL5 is a mitochondrial and cytosolic enzyme that activates long-chain fatty acids, particularly those with a preference for saturated and monounsaturated fatty acids, by converting them into acyl-CoA derivatives. ACSL5 is expressed in tissues like the small intestine, liver, and skeletal muscle, where it supports energy production, lipid absorption, and storage. This enzyme plays a crucial role in directing fatty acids toward oxidation or triglyceride synthesis, depending on metabolic demands, and is essential for maintaining energy homeostasis during fasting or high-fat diets. Dysregulation of ACSL5 has been implicated in metabolic disorders, such as obesity, diabetes, and non-alcoholic fatty liver disease, as altered fatty acid activation can lead to lipid accumulation and insulin resistance. ACSL5’s dual localization and specificity underscore its adaptability in regulating systemic and cellular lipid metabolism under diverse metabolic conditions.
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