Acyl-CoA Dehydrogenase Family Member 9 (ACAD9) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Acyl-CoA Dehydrogenase Family Member 9 (ACAD9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230062
tested applications
ELISA, WB, IHC
Description
ACAD9 Antibody is a Rabbit Polyclonal against ACAD9.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Dehydrogenase Family Member 9 (ACAD9) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H845 |
| Gene ID | 28976 |
| OMIM | 611103 |
| Alias | MC1DN20,NPD002 |
| Background | Antibody anti-ACAD9 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ACAD9 is a mitochondrial enzyme essential for the β-oxidation of long-chain fatty acids and the assembly of mitochondrial respiratory chain complex I. It functions as a dehydrogenase, catalyzing the first step in the oxidation of long-chain acyl-CoA substrates, generating energy and maintaining lipid homeostasis. ACAD9 is also a critical assembly factor for complex I, facilitating the proper formation and function of this key component of the electron transport chain. Its dual role in fatty acid oxidation and complex I assembly makes ACAD9 indispensable for mitochondrial energy metabolism. Mutations in the ACAD9 gene are associated with complex I deficiency, a severe mitochondrial disorder that can lead to cardiomyopathy, encephalopathy, and metabolic crises. The high expression of ACAD9 in energy-demanding tissues such as the heart, liver, and brain reflects its importance in maintaining mitochondrial function and energy production, positioning it as a vital enzyme in cellular metabolism.
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