Acyl-CoA Dehydrogenase Family Member 9 (ACAD9) Antibody

Este producto es parte de ACAD - Acyl-CoA Dehydrogenase
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Acyl-CoA Dehydrogenase Family Member 9 (ACAD9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038001
tested applications
ELISA, WB, IHC

Description

Rabbit Polyclonal against the ACAD9 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acyl-CoA Dehydrogenase Family Member 9 (ACAD9)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by Protein A/G column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
MC1DN20,NPD002
Background
Antibody anti-ACAD9
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

ACAD9 is a mitochondrial enzyme essential for the β-oxidation of long-chain fatty acids and the assembly of mitochondrial respiratory chain complex I. It functions as a dehydrogenase, catalyzing the first step in the oxidation of long-chain acyl-CoA substrates, generating energy and maintaining lipid homeostasis. ACAD9 is also a critical assembly factor for complex I, facilitating the proper formation and function of this key component of the electron transport chain. Its dual role in fatty acid oxidation and complex I assembly makes ACAD9 indispensable for mitochondrial energy metabolism. Mutations in the ACAD9 gene are associated with complex I deficiency, a severe mitochondrial disorder that can lead to cardiomyopathy, encephalopathy, and metabolic crises. The high expression of ACAD9 in energy-demanding tissues such as the heart, liver, and brain reflects its importance in maintaining mitochondrial function and energy production, positioning it as a vital enzyme in cellular metabolism.

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