Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antibody
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-ACADM
proveedor
Abbexareference
abx432269Tested Applications
P-ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ACADM Antibody is a Goat Polyclonal antibody against ACADM.
Background
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB, IHC
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACADM
dry ice
No
availability
Shipped within 5-10 working days.
alias
ACAD1,MCAD,MCADH
NCBI accession
NP_000007.1, NP_001120800.1
note
Concentration: 0.5 mg/ml -
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