Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antibody
637€ (100 µl)
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935106861
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name
Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110809
tested applications
ELISA, WB
Description
Acyl-Coenzyme A Dehydrogenase, C-4 To C-12 Straight Chain Antibody is a Rabbit Polyclonal antibody against Acyl-Coenzyme A Dehydrogenase, C-4 To C-12 Straight Chain.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11310 |
| Gene ID | 34 |
| NCBI Accession | NP_000007.1, NM_000016.5 |
| OMIM | 201450 |
| Alias | ACAD1,MCAD,MCADH |
| Background | Antibody anti-ACADM |
| Status | RUO |
Descripción
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
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