Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody (Biotin)
169€ (20 µg)
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935106861
info@markelab.com
name
Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx307635
tested applications
ELISA
Description
ACBD5 Antibody (Biotin) is a Rabbit Polyclonal against ACBD5 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Binding Domain Containing 5 (ACBD5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5T8D3 |
| Gene ID | 91452 |
| NCBI Accession | NP_001035938.1, NM_001042473.3 |
| OMIM | 616618 |
| Alias | RDLKD |
| Background | Antibody anti-ACBD5 |
| Status | RUO |
Descripción
ACBD5 is a peroxisomal protein that serves a key role in lipid metabolism by transporting very-long-chain fatty acyl-CoA into peroxisomes for beta-oxidation. It acts as a tether between peroxisomes and the endoplasmic reticulum (ER) by interacting with the ER-resident protein VAPB, enabling efficient lipid exchange between these organelles. ACBD5 is essential for maintaining peroxisomal function and lipid homeostasis, with significant implications for energy production and membrane lipid composition. Mutations in ACBD5 are associated with peroxisomal disorders, such as Zellweger spectrum disorders, which are characterized by defects in lipid metabolism. ACBD5 is also being studied for its potential role in modulating inflammation and oxidative stress in metabolic diseases.
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