Activity-Dependent Neuroprotector Homeobox Protein 2 (ADNP2) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Activity-Dependent Neuroprotector Homeobox Protein 2 (ADNP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037642
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the ADNP2 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Activity-Dependent Neuroprotector Homeobox Protein 2 (ADNP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_055728.1 |
| Alias | ADNP homeobox 2,ZNF508,Zinc finger protein 508 |
| Background | Antibody anti-ADNP2 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Activity-dependent neuroprotector homeobox protein 2 (ADNP2) is a homolog of ADNP, part of the homeobox-containing transcription factor family involved in chromatin remodeling and gene regulation critical for cellular and neuronal processes ADNP2 is implicated in neurogenesis, neuronal survival, and synaptic plasticity, with studies indicating its role in brain development and maintenance of central nervous system integrity While its functions overlap with ADNP, emerging evidence suggests additional distinct roles in cellular proliferation, differentiation, and response to oxidative stress ADNP2 interacts with chromatin-modifying complexes, regulating genes associated with neuronal health and cognitive function Dysregulation of ADNP2 has been linked to neurodevelopmental disorders, neurodegenerative diseases like Alzheimer’s, and impaired synaptic function Recent findings also connect ADNP2 to cancer biology, where it can regulate cell cycle progression and survival pathways Moreover, ADNP2 may influence immune system modulation, participating in cellular stress responses and transcriptional networks that control neuronal and immune homeostasis
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