Activin A Receptor Type 2B (ACVR2B) Antibody

Este producto es parte de ACVR - Activin A Receptor Type
Activin A Receptor Type 2B (ACVR2B) Antibody

Pida mas información

935106861

info@markelab.com

Precio

237.5€ (50 µl)

Antibody anti-ACVR2B

proveedor

Abbexa

reference

abx320457

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

ACVR2B Antibody is a Rabbit Polyclonal against ACVR2B.


Background

ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Activin A Receptor Type 2B (ACVR2B)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IHC


purification

Antigen Affinity Chromatography.


buffer

PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.


size 1

50 µl


size 2

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ACVR2B


dry ice

No


availability

Shipped within 5-10 working days.


alias

Activin receptor type IIB,ACTR-IIB


NCBI accession

NP_001097.2, NM_001106.3


note

This product is for research use only.


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