Activin A Receptor Type 2B (ACVR2B) Antibody
![Activin A Receptor Type 2B (ACVR2B) Antibody](/_next/image?url=https%3A%2F%2Fmarkelab.com%2Fpublic-files%2Fimages%2FAntibody-Box.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
250€ (50 µl)
Antibody anti-ACVR2B
proveedor
Abbexareference
abx214684Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
ACVR2B Antibody is a Rabbit Polyclonal against ACVR2B.
Background
ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Activin A Receptor Type 2B (ACVR2B)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Antigen Affinity Chromatography.
buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACVR2B
dry ice
No
availability
Shipped within 5-10 working days.
alias
Activin receptor type IIB,ACTR-IIB
uniprot id
note
This product is for research use only.
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