Activin A Receptor Type 2B (ACVR2B) Antibody

Este producto es parte de ACVR - Activin A Receptor Type
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260€ (50 µl)

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935106861
info@markelab.com
name
Activin A Receptor Type 2B (ACVR2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx213742
tested applications
ELISA, IHC

Description

ACVR2B Antibody is a Rabbit Polyclonal against ACVR2B.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Activin A Receptor Type 2B (ACVR2B)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/1000 - 1/2000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13705
Gene ID
93
Alias
Activin receptor type IIB,ACTR-IIB
Background
Antibody anti-ACVR2B
Status
RUO

Descripción

ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.

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Activin A Receptor Type 2B (ACVR2B) Antibody

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