Activating Transcription Factor 6 Beta (ATF6B) Antibody
637€ (100 µl)
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935106861
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name
Activating Transcription Factor 6 Beta (ATF6B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110787
tested applications
ELISA, WB, IHC, IF/ICC
Description
Activating Transcription Factor 6 Beta Antibody is a Rabbit Polyclonal antibody against Activating Transcription Factor 6 Beta.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Activating Transcription Factor 6 Beta (ATF6B) Immunogen: Human ATF6B. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99941 |
| Gene ID | 1388 |
| NCBI Accession | NP_001129625.1, NM_001136153.1, NP_004372.3, NM_004381.4 |
| OMIM | 600984 |
| Alias | ATF6beta,CREB-RP,CREBL1,G13 |
| Background | Antibody anti-ATF6B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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The endoplasmic reticulum (ER)-transmembrane proteins, ATF6 alpha (ATF6) and ATF6 beta (ATF6B), are cleaved during the ER stress response (ERSR). The resulting N-terminal fragments of both ATF6 isoforms, which have conserved basic leucine-zipper and DNA binding domains but divergent transcriptional activation domains, translocate to the nucleus where they bind to ER stress-response elements (ERSE) in ERSR, such as Bip/GRP78. This antibody could recognize ATF6 beta (110kd) and its cleaved forms(60,80kd )(PMID: 11256944)
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