Actinin alpha-2 / 3 Cell ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
513.5€ (96 tests)
Elisa kits for ACTN2
proveedor
Abbexareference
abx595743Tested Applications
ELISAreactivity
Human, Mouse, Ratstatus
RUOclonality
Descripción
Actinin alpha-2/3 Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Background
ACTN2 encodes alpha-actinin-2, a muscle-specific isoform of the actinin family, expressed predominantly in cardiac and skeletal muscle tissues. It functions as a structural component of the sarcomere, anchoring actin filaments to the Z-discs and contributing to the maintenance of sarcomere integrity during muscle contraction. ACTN2 also plays a role in signal transduction by interacting with a variety of signaling and cytoskeletal proteins, modulating muscle development and repair. Mutations in ACTN2 are associated with cardiomyopathies, including hypertrophic and dilated cardiomyopathy, where impaired sarcomeric organization leads to reduced cardiac function. Its critical role in sarcomere structure and interaction with signaling pathways highlights its importance in maintaining muscle function and responding to mechanical stress.
Características del producto
category
ELISA Kits
immunogen target
Actinin alpha-2/3
reactivity
Human, Mouse, Rat
detection method
Colorimetric
size 1
96 tests
alias
ACTN2,CMD1AA,CMH23,MYOCOZ,MPD6
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACTN2
dry ice
No
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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